Amlodipine (as besylate, mesylate or maleate) is a long-acting calcium channel blocker (dihydropyridine class) used as an anti-hypertensive and in the treatment of angina. Like other calcium channel blockers, amlodipine acts by relaxing the smooth muscle in the arterial wall, decreasing peripheral resistance and hence reducing blood pressure; in angina it increases blood flow to the heart muscle.
Amlodipine is marketed as Dailyvasc in the Philippines by Xeno Pharmaceuticals, and by Pfizer as Norvasc in North America, Australia and some European countries, and as Istin in the United Kingdom. Generic brands (sold under names such as Perivasc in Australia) are also available.
Amlodipine is marketed as Dailyvasc in the Philippines by Xeno Pharmaceuticals, and by Pfizer as Norvasc in North America, Australia and some European countries, and as Istin in the United Kingdom. Generic brands (sold under names such as Perivasc in Australia) are also available.
Side effects
Some side effects[1] of the use of amlodipine may be:Very often: peripheral edema (feet and ankles) - in 1 of 10 usersOften: dizziness; palpitations; muscle-, stomach- or headache; dyspepsia; nausea - in 1 in 100 usersSometimes: blood disorders, development of breasts in men (gynecomastia), impotence, depression, insomnia, tachycardia - in 1 in 1,000 usersRarely: erratic behavior, hepatitis, jaundice - in 1 in 10,000 usersVery rarely: hyperglycemia, tremor, Stevens-Johnson syndrome - in 1 in 100,000 users
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